BREAST CANCER BASE

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Affect the prognosis of breast cancer in many solid, and their mutual relations are complicated, it should be integrated various factors to estimate a patient's prognosis.

The main prognostic factors are the following :

(1) - Clinical hardship;

(2) age : the youngest general cases that the rapid development of tumors, lymph node metastasis, the prognosis is poor;

(3) The size of the primary lesion and local infiltration : in the absence of regional lymph nodes and distant metastasis circumstances, the greater the primary lesion and local infiltration more serious, the worse the prognosis;

(4) lymph node metastasis;

(5) the pathology of the tumor type and degree of differentiation;

(6) steroid hormone receptor;

(7) the rate of cell proliferation and DNA content;

(8) oncogene.

The etiology of breast cancer has not yet been settled, it truly can be used to prevent an extremely limited means, but careful to make several breast cancer risk reduction measures are possible, such as puberty appropriate restraint fat and animal protein intake, increasing physical activity and encourage breastfeeding babies, menopause women are advised to avoid using estrogen after menopause appropriate increasing physical activity, controlling total calorie and fat intake, avoid unnecessary exposure to radiation.

Application of surgical treatment of breast cancer has a long history, the scope of operations changes. In recent years, due to the development of breast cancer with a new concept, that the incidence of breast cancer since starting serves systemic disease, in order to preserve the appearance of breast and upper limb function, various smaller than the removal of the whole breast surgery and comprehensive application of chemotherapy and radiotherapy. In Europe and the United States and other countries, radical or modified radical mastectomy operation of the application is on the decrease and partial resection surgery and radiotherapy in the treatment of patients with breast cancer cases has reached 20% to 30%, while considering breast reconstruction. The current treatment of breast cancer, has not only satisfied whether malignant tumor and metastasis, but called for postoperative treatment and prognosis for uses such as observations vessels, lymphatic invasion, receptor assay and flow cytometry and DNA content of the cell cycle phase the distribution, application of monoclonal antibodies for diagnosis and treatment. In recent years, with Oncogene the in-depth study and found that many of the prognosis of breast cancer-related genes. Expected in the near future, one can detect through all patients to determine the prognosis, and for a high degree of risk of relapse cases choose the appropriate treatment to improve the cure rate.

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