BREAST CANCER BASE

Breast cancer etiology Breast cancer Etiology Breast cancer causes more relevant factors, common risk factors are : 1. Age : In women, incidence rates increa...

The definition of early breast cancer Previous to breast tumors smaller than 2 cm, clinical stage I and without lymph node metastasis of breast cancer Phase II of EBC, Western li...

Female breast cancer is the most common cancer, second only to the incidence of cervical cancer. Breast cancer incidence and mortality were Western Europe, ranking first in North America, Asia, Latin America, Africa, the lowest in recent years, statistics show an increasing trend.

[Causes]
Like other breast cancer, the real cause is not yet clear. But through basic and clinical research, a large number of epidemiological investigation, analysis, known to many factors can affect the development of breast cancer, the more extensive and in-depth study of the endocrine, genetic and viral pathogens of the three factors.

One, sex hormone disorder : estrogen (estradiol in particular), prolactin in animal experiments have proved to be carcinogenic. Major breast cancer among women occurred in a good pre-menopausal, and after early menarche, late menopause women. When both sides of ovarian development or for surgical resection, the breast cancer incidence rate has declined markedly. With the addition of glucocorticoid metabolism disorder and exogenous estrogen has a certain relationship.

2, genetic factors : a family history of breast cancer in women, the incidence of relative risks, in premenopausal and postmenopausal were 2.4 and 1.7 (for a normal women). Especially the mother and relatives sisters have occurred in pre-menopausal women bilateral breast cancer, their 40-year-old former cancer greatly increase the risk.

3, the virus carcinogenic in animal experiments have confirmed, but the breast milk within the organization and also see the B-type virus-like particles, but it was also a negative attitude, and it has no sufficient epidemiological evidence to Demonstrated it.

It was also suggested that the incidence of breast cancer and lifestyle, diet, nutrition, caloric, closely related to obesity.

[Pathological classification]
Breast cancer is more complex patterns, many types, often with a cancer tissue, and even within a section with two or more types also exist. The current international and domestic pathological classification of breast cancer in practical applications are not yet uniform. Domestic pathology of breast cancer are as follows :

A non-invasive cancer : cancer refers to the earliest stage of breast lesions confined to the catheter or acinar, no breakthrough basement membrane, said non-invasive.
1), lobular carcinoma in situ : originated in lobular and ductal not shoot ductal cancer, breast cancer accounts for about 1.5%. Cut surface translucent pink harder granular, most lesions showed multifocal, cell size, morphology consistent, but disarrangement, the catheter around the basement membrane integrity, often involving bilateral and slow growth.

2) intraductal carcinoma : occurred in the center tube carcinoma in situ lesions can affect the scope or catheter was multi-center, scattered distribution, granular cut surface with small gray or pale yellow, like the skin acne-like content.

2, the early stage : from non-invasive cancer to invasive cancer is a gradual process of development. After infiltrating during the early stages, according to the form, into the second category.
1) Early invasive lobular carcinoma : lobular carcinoma in situ through the basement membrane to Intralobular interstitial infiltration, but not invasive lobular to scope.
2) Early invasive ductal carcinoma : ductal carcinoma in a small basement membrane cell breakthrough catheter to interstitial infiltration, but the scope of a small invasion.

3, invasive carcinoma to the wider interstitial infiltration, various forms of cancer tissue morphology and interstitial phase mixed picture. Invasive cancer is divided into special-invasive cancer and invasive non-specific cancer. Invasive non-specific cancer accordance with cancer and stromal proportion divided into : pure cancer, cancer hard, medullary carcinoma.

1) non-invasive cancer special type :
① cancer simple : see more about breast cancer by more than half. The main quality cancer and stromal components similar to cancer cells often gather into small nest, flaked or thick cords.
② hard cancer : breast cancer accounts for about 10% of the total around the main cancer less quality, more interstitial features. Small size, texture tough cross-section of white porcelain, the cancer risk was crab-foot to the surrounding infiltration.
③ medullary cancer : breast cancer total about 10 ~ 20%, cancer of the main quality, interstitial less. Tumor size up huge, gray and white plane, the center often Department necrosis. According interstitial infiltration of lymphocytes in varying degrees, can be divided into two subtypes : lymphocyte infiltration of non-small yellow-medullary carcinoma, were infiltrating more typical medullary carcinoma. The latter prognosis is good, and often included within the special-invasive.

2) a special type of invasive cancer
① papillary carcinoma : large intraductal carcinoma, little by the big intraductal papilloma evolution. 50 were found to have ~ 60-year-old women, single or mass-fat, some nipple discharge, the most courageous, discharge smear can find cancer cells. Brown convey to cut red nodules, tumor, the presence of pink carrion-like papillary or organizations. This slow-growing cancer, the late transfer. When the real cancer for more than half performance gland-like structure, may be diagnosed as adenocarcinoma.
② mucinous carcinoma : also known as plastic-like cancer, less see. Age of onset, slow growth, state clearly that plane ACCC10012 translucent objects, cancer tissue containing mucus rich, less vicious, less armpit lymph node metastasis see.
③ eczema carcinoma : also known as Paget's disease. This form of cancer characterized by : nipple, areola skin was eczema-like skin changes and there is a large and are characteristic of Paget's cells. This merger of the majority of cancer ductal carcinoma and lobular carcinoma in situ, part of the invasive ductal cancer.

The causes of breast cancer and the factors Breast cancer is the breast ductal epithelial cells in various internal and external factors of cancer, the cells are deprived of the norma...

Breast cancer is the cause of what The exact cause of breast cancer has not been determined. Because breast cancer etiology may relate to a variety of factors, it can only sa...

Affect the prognosis of breast cancer Solid - Affect the prognosis of breast cancer in many solid, and their mutual relations are complicated, it should be integrated various factors to ...

Historical overview of breast cancer Breast cancer of the breast ductal epithelial cells in various internal and external factors of cancer, the cells are deprived of the norma...

Breast cancer before surgery which required preparation? Breast cancer surgery made all the preparations for major surgery routine check of patients with heart, liver, lung, kidney and other organ...

What is invasive breast cancer and non-invasive breast cancer Invasive cancer and non-invasive breast cancer is the histological classification, according to its morphological characteristics identified...

Breast cancer detection rate of only 1% of the youngest aged only 17 patients

Breast cancer patients how to take treatment