BREAST CANCER BASE

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Outlined
The majority of breast cancer origins of breast tissue (breast cancer), and a minority can be derived from the various non-breast epithelial organizations (sarcoma), the duality can be seen mixed in carcinosarcoma. The incidence of breast cancer in China after cervical cancer, the incidence of crowd 23/10 10000; With the cancer accounted for the 7 ~ 10%.

Etiology
The cause of breast cancer is not completely clear, have confirmed the incidence of certain factors still exist in a number of controversies. Pre-menopausal and post-menopausal estrogen stimulation is the obvious factors of breast cancer. In addition, genetic factors, diet, physical and chemical factors outside of certain benign breast disease and breast cancer is certainly happen.

Symptoms
Breast cancer is the earliest manifestation of this is there risk of breast single, painless and were sexually growth of small lumps. Mass at the upper outer quadrant see the most, followed by nipple and areola area and within the upper quadrant. For more consciously without symptoms, tumor patients often inadvertently (such as bathing, dressing and undressing) found.

A small number of patients can have different degrees of tenderness or stimulate and nipple discharge. Masses of faster growth, invade surrounding tissue and can cause breast contour changes, there was a series of signs. Such as : skin tumor surface depression; Neighboring papillary carcinoma of the nipple may lead to cancer direction; Such inverted nipple. Cancer greater will enable the entire breast tissue contraction, the mass was obviously protruding. Cancer continues to grow, forming a so-called "orange peel" for change. These are important signs of breast cancer.

The development of advanced breast cancer, skin surface violations, skin nodules, worse skin ulceration of ulcer formation. Cancer violations to the deep, invasive thoracic fascia and muscle, causing chest wall masses in fixed and difficult to promote.
Lymph node metastasis of breast cancer more performance for the ipsilateral axillary lymph nodes, the beginning of the casual, painless, hard-quality, the relatively small number can be driven; After the swelling of lymph nodes increase in the number of group tours mutual adhesion, or axillary skin and deep tissue adhesion and fixed. There will be a small number of patients contralateral axillary lymph node metastases.
Breast cancer metastasis to lung, there will be chest pain, shortness of breath, pleural effusion; Transfer vertebra, the injured area was pain there even paraplegia; Liver metastases, there will be jaundice, liver size, etc..
We need to be aware that some special form of breast cancer (breast and nipple inflammatory carcinoma eczema), the law of its development and clinical performance and breast cancer is different.

Check
For nature to be determined and highly suspicious of breast cancer tumors, the biopsy is of important significance in the differential diagnosis.

Treatment
Breast cancer treatment methods and more measures, including surgery, radiotherapy, chemotherapy and endocrine therapy. Most currently used mainly of surgical treatment.
1. Surgical treatment : radical resection surgery for breast cancer therapy has been a century of history of breast cancer is still the primary means of treatment, but there is no right of early axillary lymph node metastasis of breast cancer in most satisfied with the effect.
2. Radiation therapy : usually used after surgery to prevent recurrence. For patients with advanced breast cancer radiation therapy, the tumor can reduce, or even can not transfer surgery for breast cancer surgery can be removed. For isolated lesions of local recurrence and breast cancer bone metastases have a palliative effect. But for early breast cancer do without lymph node metastasis in patients without conventional radiotherapy for treatment, in order to avoid damage to the body's immune function.
3. Hormonal therapy : Where inappropriate surgery or radiotherapy in the treatment of advanced primary breast cancer, estrogen receptor-positive determination, either singly or in combination endocrine therapy. By using drugs and by means of menstruation varies.
4. Chemical treatment : chemical anticancer drug treatment is a necessary systemic adjuvant therapy (cyclophosphamide, Lomustine, chlorambucil).

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