Breast common transfer
Breast cancer prone position which transfer Breast cancer and other tumors, often through the blood or lymphatic Road spread to other parts. (1), lymph node metastasis : axillary lymp...
Breast cancer metastasis identifiable University of California researchers have developed a new identification of metastatic and non-metastatic breast cancer cells, published in...
All cancer metastasis is an important one pathological changes. In accordance with the mobile cancer in different ways and can be divided into four categories : local invasion, metastasis, hematogenous metastasis, lymph node metastasis. “局部浸润”是指癌细胞发生恶性增殖,突破了原发器官周边组织的限制,癌细胞从原发灶直接侵入邻近组织器官。 "Cultivation" is in the chest, abdomen and other parts of internal organs (such as the lungs, stomach, liver, etc.) into the cavity cancer, the cancer cells to the body cavity off in the face of growing other organs, forming a broad spread. "Hematogenous metastasis" means cancer cells have entered the blood, with blood circulation spread to the whole body. "Metastasis" refers to enter lymphatic cancer, with lymph return transfer process.
As the breast is an organ surface, is rich with lymphatic and vascular, breast cancer metastasis is the main mode local infiltration, blood transfer and lymph node metastasis.
(1) local infiltration : Most breast cancer cells originated in the breast ductal epithelial cells to the early spread along the glands of growth. Foci were further breakthroughs in the development of the glandular epithelial basement membrane along fascial space infiltration expansion violations skin, lymphatic and thorax deep muscle tissue. Violations of ligament cancer, breast suspensory ligament can reduce occurrence of "dimple - like" skin sag; Lymphatic cancer and invasive tumor thrombus formation, lymphatic flow obstruction caused skin edema, typical of the "Orange" for skin changes; Within lymphatic cancer continue to develop and become skin " satellite nodules "; cancer violations of the small blood vessels deep, partially blocked blood can form "inflammatory carcinoma," "telangiectasia carcinoma," "erysipelas carcinoma." Increased cancer tumor after partial insufficiency, tumor necrosis occurred center can form cancerous ulcer.
(2), lymph node metastasis : the lymph node metastasis of breast cancer risk high, the most common site of metastasis was the ipsilateral axillary lymph nodes, followed by the ipsilateral internal mammary lymph nodes, can be extended to late ipsilateral subclavian lymph nodes, or even contralateral subclavian lymph nodes. Lymph node metastasis of cancer of the main manifestations of the way in which the transfer after the lymphadenopathy stiffen, and even integrated into the Mission, fixed. Advanced enlarged lymph nodes, there may be blood vessels and nerve compression performance. Because lymphatic eventually will undergo thoracic cavity injection of intravenous catheters, but also lymphatic metastasis and hematogenous metastasis of breast cancer together constitute a distant organs (lung, liver, brain, etc.) transfer.
(3) hematogenous metastasis : blood transfers mainly caused distant tissues and organs of metastatic cancer, there may be a corresponding organ disease signs and symptoms. If lung metastases, there will be X-ray films, the shadow of multiple nodules; Bone metastases in radiation radionuclide bone scan discovered more fat accumulation of radioactive shadow; Brain metastases, there may be signs such spirit and the lesions.
As of early breast cancer is the transfer characteristics, in the diagnosis and treatment process, shortening the waiting time between the prognosis of patients with important significance.
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