BREAST CANCER BASE

Breast cancer Adrenalectomy Postmenopausal women who have estrogen as a major source of the secretion of adrenal precursors. Removal of bilateral adrenal treatment of a...

2006 NCCN guidelines for advanced or recurrent breast cancer endocrine therapy For ER / PR positive only bone / tissue transfer or asymptomatic visceral metastasis in patients with breast cancer, dealing with the follow...

    乳腺癌的生长与卵巢的内分泌功能有关,因此消除双侧卵巢功能便成为治疗绝经前或绝经1年左右的晚期或复发性乳腺癌的一项重要的内分泌疗法.卵巢切除有效与否主要取决于乳腺癌是否是雌激素依赖性的,只有雌激素依赖性的乳腺癌才是卵巢切除的适应症,否之疗效不会明显. 临床一般把乳腺癌腋窝淋巴结有转移或平常来月经时乳房明显胀痛视为雌激素依赖性.绝经后和年轻的病人不适合作预防性卵巢切除术.在未经选择的乳腺癌病例中,卵巢切除的有效率为25%~37%.在有效的病人中,平均缓解期为10~14个月、平均生存时间达31个月、5年生存率达19%；而在无效的病例中平均生存时间仅为9个月、 can not survive five years.雌激素受体阳性的病人，去势后疗效明显增高，有效率可达60%~80%；而雌激素阴性者有效率仅为10%。 General conditions for the poor, can hardly tolerate the operation, the use of radiation castration.
The first use of the law should be based on the anatomical location of ovarian confirm its projection surface. If the location of the normal uterine, ovarian surface projection in the supine position with the umbilical anterior superior iliac spine connection with the mid-point of pubic symphysis midpoint midpoint of the line. If abnormal uterine position can be based on the location of the uterus adjusted accordingly. Design irradiation, the above surface projection, based on ultrasound or CT correction to the bilateral ovarian projection for ovarian midpoint, located 12 cm × 1 cm or 10 cm x 5 cm radiation field, 60 or high-energy radiation, absorbed dose ovarian site 2000CGY/10 times / 2 weeks that would achieve the objective of castration. Generally considered two castration surgery considerable, but surgery for ovarian results more reliable and complete and produce faster time; Radiotherapy and effectual time to castration until 6 to 8 weeks, if eight weeks after invalid as a failure. Radiation effects of castration vaginal smears can be judged. Radiotherapy ovarian function castration to eliminate the effect is not permanent, about 1 / 3 of patients after radiotherapy castration still menstruation. It is of advanced breast cancer patients unless it can not tolerate the surgery, seeking castration should be first choice ovariectomy.

Breast cancer endocrine treatment which? Breast cancer and endocrine (particularly ovarian) is close to endocrine therapy in the disease only palliative effect, but in the conserva...

Breast hyperplasia and the occurrence of breast cancer and endocrine function is what ties The incidence of breast hyperplasia more complex reasons, the overwhelming majority of the body with estrogen and progesterone secretion of ...

The first phase of breast cancer after treatment of long-term complications Female breast cancer has become common malignancy, with the census and the importance of screening technology continues to improve, more and...