BREAST CANCER BASE

    乳腺癌治疗方法较多，包括手术、放射治疗、化疗、内分泌治疗、免疫治疗、中医药治疗。 Clinical right early and mid-surgery patients to the first choice, advanced to the patient for treatment properly.

According to the clinical stage of breast cancer, commonly used in the treatment of the following programs :
The first phase of breast cancer : mainly radical surgery. Intraoperative and postoperative pathologic examination, such as axillary lymph node metastasis, we should make supraclavicular lymph nodes and parasternal regional radiation therapy. Recently some scholars advocated for early breast cancer Breast only partial resection or simple excision and axillary lymph node dissection group, or will retain the pectoralis major modified radical mastectomy, or supplemented by postoperative radiation therapy.

Phase II breast cancer : radical surgery. If breast cancer is located at the medial quadrant, could consider expanding radical operation. Postoperative radiotherapy and chemotherapy or endocrine therapy.

Phase III breast cancer : in principle, be used mainly to radiotherapy comprehensive treatment. Some people advocate for radiotherapy first, then surgery. A pair of subcutaneously into the ulcer can be considered for a simple mastectomy surgery. After supplemented by chemotherapy and endocrine therapy.

4 breast cancer : endocrine, chemical drugs and herbal treatment mainly to relieve pain and prolong life.

A surgery
1, with radical mastectomy : removal of the entire breast, including around 3-5 cm tumor of the skin and fatty tissue around the breast and chest, small muscle and subclavian and axillary all the adipose tissue and lymph nodes. Advocate thin flap surgery to avoid possible subcutaneously into extrusion, in order to avoid the proliferation of cancer cells.

Two, expanding Radical Surgery : In addition to the above-mentioned radical resection of the organization, will be the second ipsilateral breast, three, four rib, internal mammary artery and vein and parasternal lymph nodes and chest muscles and breast size together en bloc. Mainly for breast medial quadrant and the Central District of breast cancer.

3, modified radical mastectomy : apply to Ⅰ, Ⅱ early patients with radical operation-mainly divided into reservations or pectoralis major reservations pectoralis minor muscles, axillary dissection with the general radical operation.

Second, radiotherapy
Electronic accelerator, and 60 for the treatment of cobalt irradiation in vitro, with the aim of killing subcutaneously into primary and metastatic cancer of the lymph nodes. After radiotherapy, some subcutaneously into narrow, not the original surgery for breast cancer can be transformed into surgery. Clinical more commonly used in the axillary lymph nodes three more patients after the transfer, or medial, with the central focus of axillary lymph node metastasis in patients after means. For bone metastases patients, radiation therapy to reduce local pain better results.

3, endocrine therapy
Since the 1930s, advanced breast cancer palliative treatment of endocrine surgery example, the ovary, adrenal, pituitary surgery and to meet some of the patients to alleviate symptoms. 1980s endocrine therapy, surgery to replace drug trends. Most endocrine therapy for advanced breast cancer in palliative care, but also as accompanied by the mid-axillary lymph node metastases in patients one treatment method. Simple common drugs as follows :

1, tamoxifen (TAM) : Estrogen receptor inhibitors. Estrogen receptor (ER) and progesterone receptor (PR) positive effects of acupuncture patients. For postmenopausal, advanced breast cancer. The treatment of soft tissue transfer superior to bone metastases, the general 20mg / day.

2, amino derivative Mian can (AG) : Quasi adrenalectomized drugs, plus hydrocortisone the loose, with the former indications. Right bone, offal transfer of a certain effect, the general 50mg / day.

3, A to one word : on the bone, soft tissue, visceral metastasis in patients postmenopausal women with advanced application, particularly ER ( ), PR ( ), 20mg dose / time, four times a day.

4, MPA : with indications ago, more than on the pharmacological drugs, commonly used doses of 500mg - 1000mg / day. Endocrine therapy with chemotherapy, the treatment of advanced breast cancer. Endocrine agents could meet as a surgical adjuvant therapy use, a certain side effects, we must strengthen observation. As for the ER ( ), PR ( ) in postmenopausal patients.

4, chemical drugs
After applied to a lymph node metastasis of ER and PR-negative patients or palliative surgery in patients late. Or before, during or after application, to prevent extrusion operation and proliferation. Clinical regular joint CMF chemotherapy, CMFVP, CAF program. CTX100mm / day x 14, Oral (or CTX600mg/m2, 1,8 days intravenous), MTX40mg/m2, Japan intravenous 1,8, 1,8 5Fu600mg/m2 first day intravenous injection, on the 28th of each repeat, sharing 6 — 12 cycles. CMFVP program of CMF program increases VCR1mg/m2 / week, diluted intravenous drip, Pred 30mg/m2 / day, 15 days of oral diminishing. CAF : CTX400mg/m2 section on the 1st intravenous injection, the first 1,8 5Fu400mg/m2 intravenous ADM40mg/m2 Day, a day intravenous injection, on the 28th of each repeat, for a total of eight courses.化疗期间注意化疗药物引起的局部与全身毒副反应，尤应密切注意药物对骨髓的抑制，白细胞少于4000，血小板小于8万停药，化疗期间需加强支持治疗。

5, Chinese medicine treatment of Hebei Tumor Hospital Fu Shan Chinese medicine developed by the Fu Shan God series anticancer agents to be effective in controlling cancer metastasis and recurrence, with radiotherapy and chemotherapy can reduce radiotherapy and chemotherapy side effects. Even with the loss surgery, radiotherapy and chemotherapy in patients with advanced opportunities, but also to control cancer growth and metastasis, less cancer pain, improve symptoms, improve quality of life and extended survival with cancer.