BREAST CANCER BASE

Androgen used for pre-menopausal or post-menopausal advanced breast cancer patients, especially combined with bone metastasis in patients better effect. Right postmenopausal advanced breast cancer before menopause than for the good of hormone receptor-positive cases have negative efficiency high.
Androgen commonly used drugs : testosterone 50 ~ 100 mg intramuscular injection, the weekly two to three times, a total of four to six grams. If six to eight weeks after no tumor response and should be regarded as invalid.
Androgen treatment with bone metastasis of breast cancer better, 75% to 80% of cases symptoms have been alleviated, 20% of cases the tumor cells, and even bone metastases can be completely disappeared and re-ossification. Metastatic bone pain have significant analgesic effect.
The side effects of androgen primarily manifested as masculine. Use 2 to 3 months after the patient may arise acne, increased secretion of the sebaceous glands, hair, hair loss, sound superior, the anal itching and other symptoms of amenorrhea. These symptoms can often stop on their own after the disappearance. In addition, it may lead to hypercalcemia and sodium retention edema.

Bone metastases of breast cancer metastasis blood seen in the second secondary to the disease. Early bone metastasis, no signs and symptoms. Late in bone metastasis, when the cancer larger damage bone, the periosteum violations or pathologic fracture formation can produce severe pain. Metastatic bone pain speaking parts fixed, intense pain, aggravated sexual characteristics. Long bone metastases can be formed pathological fractures; When spinal cancer can be transferred into the medullary cavity formation of pathological or compression fractures, spinal cord compression eventually cause paraplegia.

The new study found that advanced breast cancer patients after bone marrow transplantation, with only chemotherapy patients compared to no difference in survival rates. Officials of the American Cancer Early in February, the South African researchers of bone marrow transplantation for breast cancer patients has a positive effect on the views of the data is based on forged documents. The University of Pennsylvania Cancer Center auspices of the experiment, the researchers found that the cancer had already spread of breast cancer patients, bone-marrow transplants or receiving high-dose chemotherapy in patients with regularly in 2002 for conventional-dose chemotherapy compared to patients, survival time, and there is no difference. A total of 199 patients participated in the recent experiment. New England Center for Hematology and Medical Oncology Director Dr. John K. Erban, bone marrow transplant therapy only three weeks of time, this right applies some of the patients compared. Conventional therapy usually takes 2 years of the time, some of the patients can not be accepted. Washington Lombardi Cancer Center, Dr. Marc E. Lippman had that in the patients with advanced breast cancer treatment, doctors in the treatment program should be re-considered.

Breast cancer is the leading global context of female cancer-related death of one of the most common diseases, and bone is the most common site of metastasis. In case of bone metastases, bone structure and the normal reconstruction of the balance was broken, so that it will lead to severe bone pain. Australian researchers recently noted that the two phosphate can delay the destruction of bone and reduce the incidence of bone disease risk. Researchers in the 21 high-quality research analysis came to this conclusion. The results of their analysis shows that neither is doing breast cancer patients, or secondary to bone metastasis in patients, two phosphate bone destruction to reduce the incidence of important values, but on the best use of time has not been determined.