Why breast cancer need chemotherapy, which often use chemotherapy drugs
Chemotherapy is a cancer drug for the treatment of malignant tumors. These drugs in cell growth and reproduction of various segments of the role that inhibit or kill cancer cells. Chemotherapy drugs are cytotoxic drugs on the basis of its role in cancer cells, can be divided into non-specificity of the cell cycle and cell cycle specific drugs two categories, the former can attack all the tumor cells, whether the suspension period or period is split cells, cancer cells divide state caesura than state more susceptible to drugs kill, the cell cycle specific drugs can be selective role in the cancer cell division stage. Therefore clinical use of cell cycle specific drugs and non-specific component of the multiple drug chemotherapy drugs to enhance the effectiveness of the program.
Long time, the breast cancer treatment at home and abroad have used the radical surgery. But the 20th century since the 1950s, people of traditional radical surgery, raised objections, because although the operation control of the original cancer, but a simple surgical treatment is beyond the control of tumor recurrence and metastasis, after about half of patients with end-result of distant metastasis where treatment failure. After a lot of basic research and clinical observation shows that breast cancer is a good fat hematogenous metastasis of cancer, the blood in clinical transfer can occur earlier. According to clinical inference about half over before receiving treatment have occurred in the transfer of blood, but with some current diagnostic methods is very difficult to check out. So although the original tumor was removed completely by, and in vivo distribution of micro-metastases will continue to grow, if development can be examined to the extent, mostly belonging to the late result in undesirable consequences. According to the biology of breast cancer and immunological studies suggest that breast cancer is a multi-center characterized by the occurrence of systemic disease onset that the original tumor often a very small presence metastases. Based on the above, the treatment of breast cancer must be directed at the former cancer and blood transfer these two aspects, namely, the need for local treatment and systemic chemotherapy combined treatment method in order to fully control the development of breast cancer, both missing a breast cancer cure is difficult to achieve the objective.
Breast cancer is a solid tumor application of the most effective chemotherapy one tumor, and treatment of breast cancer anticancer drugs rapid development of new drugs continue to emerge, the effect of gradually raising. Current treatment of breast cancer better effect commonly used chemotherapy drugs are multiple : cyclophosphamide (CTX), allogeneic cyclophosphamide (IFO), 5 fluorouracil (5 FU), methotrexate (MTX), mitomycin (MMC), vincristine (VCR), Navelbine (updates), VDS (VDS), Navelbine (NVB, Navelbine), cyclohexyl nitrosourea (CCNU), Adriamycin (ADM), table adriamycin (E-ADM), pirarubicin ( THP), cisplatin (DDP), carboplatin (CBP), mitoxantrone (MIT), paclitaxel (IV) and so on.
Breast Cancer: breast cancer Treatment, cell, chemotherapy, drugs, treatment