BREAST CANCER BASE

Bone metastases of breast cancer metastasis blood seen in the second secondary to the disease. Early bone metastasis, no signs and symptoms. Late in bone metastasis, when the cancer larger damage bone, the periosteum violations or pathologic fracture formation can produce severe pain. Metastatic bone pain speaking parts fixed, intense pain, aggravated sexual characteristics. Long bone metastases can be formed pathological fractures; When spinal cancer can be transferred into the medullary cavity formation of pathological or compression fractures, spinal cord compression eventually cause paraplegia.

In general, breast common site of metastasis followed by lung and pleural and bones, and skin and soft tissue, liver and brain. Different parts of the transfer, its treatment and the treatment is not the same.

Lung breast cancer the most common site of metastasis. General performance began to dry cough and antibiotic therapy. Commonly used in the treatment of platinum-containing anticancer drugs (PDD) chemotherapy. Like CAP, NVB PDD programs. General enable more than 60% of patients with lesions in the near future to completely dissipated.

Breast cancer and endocrine (particularly ovarian) is close to endocrine therapy in the disease only palliative effect, but in the conservative advanced breast cancer treatment occupy important positions.

Endocrine therapy method : ① hormone use; ② ovariectomy; ③ adrenalectomized; ④ pituitary resection.

(1) Application of hormones : diethylstilbestrol (estrogen) : Each 5 mg orally three times a day, approximately 1 / 3 of patients effectively, especially for soft tissue tumor most noticeable. Efficacy maintain an average of 18 months, up to a few years, some more than five years. In postmenopausal four years or more patients. If there vaginal bleeding or nipple darken such phenomena, namely reductions.

Breast cancer pituitary for the treatment is a good pleura and the lung, and bone metastases and soft tissue metastases times, and liver metastases, central nervous system and the transfer of diffuse lung lymphatic infiltration of the patients showed no obvious effect. Pituitary after resection need to be supplemented glucocorticoid, pituitary and thyroid hormone vasopressin. OK pituitary patients can be removed without further Adrenalectomy, and vice versa.