BREAST CANCER BASE

Women from pregnancy, childbirth to breastfeeding, the body hormones will be major changes, early pregnancy plasma and the estrogen secretion of adrenal cortical hormones will be significantly increased, these mid-pregnancy hormone levels drop, will be up late; Breastfeeding prolactin levels will be increased significantly. While estrogen, prolactin and changes in the incidence of breast cancer is closely related. Thus, in the past that pregnancy lactating breast cancer, the condition develops quickly, and the prognosis is poor. Now advocates of breast cancer patients after treatment better not to pregnancy and lactation.

Affect the prognosis of breast cancer in many solid, and their mutual relations are complicated, it should be integrated various factors to estimate a patient's prognosis.

The main prognostic factors are the following :

(1) - Clinical hardship;

(2) age : the youngest general cases that the rapid development of tumors, lymph node metastasis, the prognosis is poor;

(3) The size of the primary lesion and local infiltration : in the absence of regional lymph nodes and distant metastasis circumstances, the greater the primary lesion and local infiltration more serious, the worse the prognosis;

Bone metastases of breast cancer metastasis blood seen in the second secondary to the disease. Early bone metastasis, no signs and symptoms. Late in bone metastasis, when the cancer larger damage bone, the periosteum violations or pathologic fracture formation can produce severe pain. Metastatic bone pain speaking parts fixed, intense pain, aggravated sexual characteristics. Long bone metastases can be formed pathological fractures; When spinal cancer can be transferred into the medullary cavity formation of pathological or compression fractures, spinal cord compression eventually cause paraplegia.

In general, breast common site of metastasis followed by lung and pleural and bones, and skin and soft tissue, liver and brain. Different parts of the transfer, its treatment and the treatment is not the same.

Lung breast cancer the most common site of metastasis. General performance began to dry cough and antibiotic therapy. Commonly used in the treatment of platinum-containing anticancer drugs (PDD) chemotherapy. Like CAP, NVB PDD programs. General enable more than 60% of patients with lesions in the near future to completely dissipated.