BREAST CANCER BASE

Women from pregnancy, childbirth to breastfeeding, the body hormones will be major changes, early pregnancy plasma and the estrogen secretion of adrenal cortical hormones will be significantly increased, these mid-pregnancy hormone levels drop, will be up late; Breastfeeding prolactin levels will be increased significantly. While estrogen, prolactin and changes in the incidence of breast cancer is closely related. Thus, in the past that pregnancy lactating breast cancer, the condition develops quickly, and the prognosis is poor. Now advocates of breast cancer patients after treatment better not to pregnancy and lactation.

Pregnancy Hormone level changes, causes the breasts to a series of physiological changes, and this change is to adapt after childbirth nursing needs. Generally speaking, since the beginning of a month of pregnancy, breast began to gradually increase the volume there, and with the increase in pregnancy and become increasingly clear, areola pigment deepening, increasing the scope and size of a grain emerging small skin nodules : nipple stiffen and increase standSeem subcutaneous varicose veins. there have colostrum.

Over the years, generally considered the same gestational age of breast cancer than the general prognosis in breast cancer patients worse. The reason why poor prognosis, because breast cancer diagnosed during pregnancy generally reached late period, the rate of positive axillary lymph nodes are often particularly high, metastatic lesions. Axillary lymph node metastasis rate of 50 ~ 80%, the five-year survival rate of 30%.
Breast cancer patients with pregnancy after six months, due to the body's endocrine changes, the breast cancer cells play a role is not reversible and therefore, termination of pregnancy will not help improve the cure rate of breast cancer during pregnancy. In addition, patients with breast cancer during pregnancy, prolactin and estrogen secreted increased, the immune defense functions decline, these changes is very conducive to the growth of cancer cells, but not termination of pregnancy can improve the prognosis.
It is worth recalling that, as long as the timely and speedy diagnosis and treatment of this disease, pregnancy outcomes in breast cancer patients will be different degrees of improvement.

Breast cancer during pregnancy and breast-feeding period known as pregnancy lactating breast cancer. Tumor Biology Research data indicate that breast cancer cells by a single mutation to begin development can be found in size (> 5 mm), it normally takes several years. Thus pregnancy lactating breast cancer concept that should be precise is the proliferation of breast cancer in the development of "coincidence" to the pregnancy and lactation.

Any women in pregnancy and lactation of breast cancer (or is suffering from breast cancer later in the pregnancy and lactation), as this "coincidence" opportunity, there are few pregnant lactating breast cancer is relatively rare in clinical, all about 5% of breast cancer cases, the age of onset - both 35-year-old (the age of the baby boomers).