BREAST CANCER BASE

Proteomics the meaning <BR> genes are the carriers of genetic information, protein is a vital function of the Executive body. Human cells contain some type of protein estimated one million to 10 million species, researchers measured only a small part of the protein sequence. Proteomics to specific cells, tissues or organs contained in the systematic study of protein based on the gene coding for the protein in all subjects, from the cells and research on the overall level of the protein component and its variation, in-depth understanding of the organisms various physiological and pathological processes. Cancer proteomics is right and normal tissue diseases (from precancerous lesions of the tumor) the difference between the expression of the protein identification and quantitative analysis. A cell disease by non-state changes to the process of tumor cells, protein expression profiles will be a series of significant changes, the use of proteomic analysis technology from cell to the overall level shows the changes, to find a specific tumor early diagnosis of biomarkers offers hope.
Proteomics technologies for protein separation and identification. Two-dimensional polyacrylamide gel electrophoresis and mass spectrometry and bioinformatics is the most commonly used of the three technologies. Protein chip technology is a high-throughput analysis method is efficient, quick advantage. Lattice can probe specific protein to capture samples of the target protein and qualitative or quantitative analysis. Antibodies are protein-chip chips, the main types of protein chip is the fastest-growing chip, it becomes increasingly mature, gradually moving towards the industrialization of the production stage. In an experiment can be parallel, high-throughput compared to the same time hundreds of cell types important function of the protein expression changes.